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Cytochrome P450 Pathway

The Cytochrome P450 Pathway, the History, and Possible Drug Interactions Tricia Siletti 13 August 2019 Current culture health care strategy calls for a variety of pharmaceuticals and herbs that are often taken together in order to try to take care of ailments. Often, these pharmaceutical drugs and herbs may interact with each other and metabolism occurs via a group of enzymes referred to as the cytochrome P450 pathway. The cytochrome P450 pathway metabolizes drugs and herbs and may either induce or inhibit their effects. This review of current research suggests that the protein enzymes that have evolved along the P450 pathway are responsible for herbal and pharmaceutical interaction and that this interaction can be influenced by one’s genetic makeup, age,...

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Roman Chamomile Charmaemelum nobile

Chamomile Chamomile, Roman and German We study Chamaemelum nobile or Roman chamomile and Matricaria recutita or German chamomile. Do not confuse chamomile with pineapple weed, which has no white petals. Note that Chamaemelum nobile is the new binomial for Anthemis nobilis, Roman chamomile.Matricaria recutita is the new binomial for Matricaria chamomilla, which is German chamomile. There are a number of species of chamomile, both naturalized and cultivated in North America, New Zealand, and Australia. Chamaemelum nobile is generally found cultivated but is naturalized in North America, Tasmania, and South Australia. Anthemis cotula or stinking mayweed is found distributed throughout New Zealand, Southern Australia, Tasmania, New South Wales, and Queensland. Anthemis arvensis or Corn Chamomile is found in New Zealand, Tasmania,...

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California Poppy Eschscholzia californica

California Poppy Nomenclature Eschscholzia californica  Family: Papaveraceae  Descriptive Characteristics Annual flower 1-2 feet in height, long stalks with grayish green foliage. Leaves are long and divided in round, lobed segments. Flowers are long stems with four wide fan shaped petals that are silky.  Colors range from yellow to orange. Flower from February to September. Fruit is slender and podlike and splits into 2 to release small black seeds.  Harvest when the flower is flowering. Propagate seeds in a sunny border outdoors. They do not transfer well so plant them where you want them. Thin the keiki so that they stand 6 to 8 in apart. Pull entire plant from ground to harvest. Dry in paper bag.  Active Constituents Eschscholtzine, californidine,...

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'Awapuhi Ginger/ Zingiber zerumbet

‘Awapuhi Ginger Zingiber zerumbet I just love the scientific name of this plant! It just rolls off the tongue.  'Awapuhi or Shampoo Ginger is a beautiful, ornamental addition to any garden. Hawaiians have been using it in their hair care for years. It provides a shine to hair and has many benefits.  Common Name(s): Shampoo Ginger Parts used: The shoots, rhizomes and inflorescence liquid are all consumable This plant is very carefree. Plant it, let it grow and watch the flowers emerge. This plant will thrive in heavy shade and waterlogged soils. In other words, it can be planted in places where most plants will not live. Practitioners’ Advice: Gently grab the stem of the flower and tilt the flower...

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Arnica Arnica montana

 Arnica flower Arnica montana Common Name(s): Arnica flos, Leopard's bane, Mountain snuff, Mountain tobacco, Sneezewort Parts used:  Root, flower Uses:  Arnica and its extracts have been widely used in folk and homeopathic medicine as a treatment for acne, boils, bruises, rashes, sprains, pains, and wounds.  It has been found to contain a collection of sesquiterpene lactones, which include helenalin, dihydrohelenalin, arnifolin, and arnicolide and are thought to be responsible for its anti-inflammatory action. Both helenalin and dihydrohelenalin have been found to reduce edema (swelling) and inflammation. When one has an injury, the site quickly becomes swollen and painful. Arnica has been shown to reduce this inflammation, thereby speeding the healing process and reducing discomfort. Dosage:  Arnica is classified as an...

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